Version 5.4
Mus musculus Protein: Ywhab
Summary
InnateDB Protein IDBP-540059.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Ywhab
Protein Name tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide
Synonyms 1300003C17Rik;
Species Mus musculus
Ensembl Protein ENSMUSP00000117125
InnateDB Gene IDBG-211991 (Ywhab)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 45 experimentally validated interaction(s) in this database.
They are also associated with 215 interaction(s) predicted by orthology.
Experimentally validated
Total 45 [view]
Protein-Protein 42 [view]
Protein-DNA 3 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 215 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003714 transcription corepressor activity
GO:0005515 protein binding
GO:0008022 protein C-terminus binding
GO:0019904 protein domain specific binding
GO:0032403 protein complex binding
GO:0042826 histone deacetylase binding
GO:0050815 phosphoserine binding
Biological Process
GO:0006605 protein targeting
GO:0035308 negative regulation of protein dephosphorylation
GO:0043085 positive regulation of catalytic activity
GO:0045892 negative regulation of transcription, DNA-templated
GO:0051220 cytoplasmic sequestering of protein
GO:0051291 protein heterooligomerization
Cellular Component
GO:0005634 nucleus
GO:0017053 transcriptional repressor complex
GO:0048471 perinuclear region of cytoplasm
GO:0070062 extracellular vesicular exosome
Protein Structure and Domains
PDB ID MGI:1891917
InterPro IPR000308 14-3-3 protein
IPR023410 14-3-3 domain
PFAM PF00244
PRINTS PR00305
PIRSF PIRSF000868
SMART SM00101
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL A2A5N1
UniProt Splice Variant
Entrez Gene 54401
UniGene
RefSeq
MGI ID
MGI Symbol Ywhab
OMIM
CCDS
HPRD
IMGT
EMBL AL591542
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca