Version 5.4
Mus musculus Protein: Bfsp2
Summary
InnateDB Protein IDBP-540110.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Bfsp2
Protein Name beaded filament structural protein 2, phakinin
Synonyms AI448593; CP49;
Species Mus musculus
Ensembl Protein ENSMUSP00000116249
InnateDB Gene IDBG-194535 (Bfsp2)
Protein Structure
UniProt Annotation
Function Involved in stabilization of lens fiber cell cytoskeleton. {ECO:0000269PubMed:12573667}.
Subcellular Localization Membrane {ECO:0000250}. Cytoplasm {ECO:0000250}. Cytoplasm, cytoskeleton {ECO:0000250}. Note=Membrane- and cytoskeleton-associated. {ECO:0000250}.
Disease Associations
Tissue Specificity Lens. {ECO:0000269PubMed:7679620}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005198 structural molecule activity
GO:0005212 structural constituent of eye lens
GO:0005515 protein binding
Biological Process
GO:0007010 cytoskeleton organization
GO:0007601 visual perception
GO:0045104 intermediate filament cytoskeleton organization
GO:0048469 cell maturation
GO:0050896 response to stimulus
GO:0070307 lens fiber cell development
Cellular Component
GO:0005737 cytoplasm
GO:0005882 intermediate filament
GO:0005886 plasma membrane
Protein Structure and Domains
PDB ID MGI:1333828
InterPro IPR001664 Intermediate filament protein
IPR002957 Keratin, type I
PFAM PF00038
PRINTS PR01248
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q6NVD9
PhosphoSite PhosphoSite-Q6NVD9
TrEMBL Q8VDD7
UniProt Splice Variant
Entrez Gene 107993
UniGene
RefSeq NP_001002896
MGI ID
MGI Symbol Bfsp2
OMIM
CCDS CCDS52903
HPRD
IMGT
EMBL AJ304860 AJ304861 BC062815 BC068172 S55549
GenPept AAB25419 AAH62815 AAH68172 CAC83161 CAC83162

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca