Version 5.4
Mus musculus Protein: Muc19
Summary
InnateDB Protein IDBP-540340.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Muc19
Protein Name mucin 19
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000125205
InnateDB Gene IDBG-176289 (Muc19)
Protein Structure
UniProt Annotation
Function May function in ocular mucus homeostasis. {ECO:0000250}.
Subcellular Localization Secreted {ECO:0000305}.
Disease Associations
Tissue Specificity Specifically expressed in sublingual salivary glands. Expressed by mucous cells of the submandibular gland and submucosal gland of the trachea. Expression is altered in sld (sublingual gland differentiation arrest) mutants. {ECO:0000269PubMed:12847143, ECO:0000269PubMed:12882755, ECO:0000269PubMed:15340121}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
Biological Process
GO:0002244 hematopoietic progenitor cell differentiation
GO:0050728 negative regulation of inflammatory response
GO:0060689 cell differentiation involved in salivary gland development
Cellular Component
GO:0005575 cellular_component
GO:0005576 extracellular region
Protein Structure and Domains
PDB ID MGI:2676278
InterPro IPR001846 von Willebrand factor, type D domain
IPR002919 Trypsin Inhibitor-like, cysteine rich domain
IPR006552 VWC out
IPR014853 Uncharacterised domain, cysteine-rich
PFAM PF00094
PF01826
PF08742
PRINTS
PIRSF
SMART SM00216
SM00215
SM00832
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q6PZE0
PhosphoSite PhosphoSite-
TrEMBL J3QMV7
UniProt Splice Variant
Entrez Gene 239611
UniGene Mm.486225
RefSeq NP_997126
MGI ID
MGI Symbol Muc19
OMIM
CCDS
HPRD
IMGT
EMBL AC101660 AY172172 AY193891 AY570293 BC061502 EU089955 EU089956 EU089957 EU089959 HM132015 HM132016 HM132022 HM132023
GenPept AAH61502 AAO38851 AAO49800 AAS77382 ABU50842 ABU50843 ABU50844 ABU50846 ADI70536 ADI70537 ADI70543 ADI70544

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca