InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Lass2

Summary

InnateDB Protein

IDBP-540354.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Lass2

Protein Name

LAG1 homolog, ceramide synthase 2

Synonyms

0610013I17Rik; AI225939; Lass2; TRH3;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000122672

InnateDB Gene

IDBG-172404 (Lass2)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 40 experimentally validated interaction(s) in this database.
They are also associated with 17 interaction(s) predicted by orthology.

Experimentally validated
Total	40 [view]
Protein-Protein	39 [view]
Protein-DNA	0
Protein-RNA	1 [view]
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	17 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003677	DNA binding
GO:0003700	sequence-specific DNA binding transcription factor activity
GO:0043565	sequence-specific DNA binding
GO:0050291	sphingosine N-acyltransferase activity

Biological Process

GO:0006355	regulation of transcription, DNA-templated
GO:0030148	sphingolipid biosynthetic process
GO:0046513	ceramide biosynthetic process

Cellular Component

GO:0005783	endoplasmic reticulum
GO:0031965	nuclear membrane

Protein Structure and Domains

PDB ID

MGI:1924143

InterPro

IPR001356 Homeobox domain
IPR009057 Homeodomain-like

PFAM

PF00046

PRINTS

PIRSF

SMART

SM00389

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-

TrEMBL

D3Z4M2

UniProt Splice Variant

Entrez Gene

76893

UniGene

Mm.181009

RefSeq

MGI ID

MGI Symbol

Cers2

OMIM

CCDS

HPRD

IMGT

EMBL

AC092202 AC140190

GenPept