InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Top2b

Summary

InnateDB Protein

IDBP-540389.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Top2b

Protein Name

topoisomerase (DNA) II beta

Synonyms

D230016L12Rik; Top-2;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000124889

InnateDB Gene

IDBG-133323 (Top2b)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 17 experimentally validated interaction(s) in this database.
They are also associated with 42 interaction(s) predicted by orthology.

Experimentally validated
Total	17 [view]
Protein-Protein	16 [view]
Protein-DNA	1 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	42 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003677	DNA binding
GO:0003918	DNA topoisomerase (ATP-hydrolyzing) activity
GO:0005524	ATP binding

Biological Process

GO:0006265

DNA topological change

Cellular Component

Protein Structure and Domains

PDB ID

MGI:98791

InterPro

IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal
IPR013760 DNA topoisomerase, type IIA-like domain

PFAM

PF00521

PRINTS

PIRSF

SMART

SM00434

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-

TrEMBL

UniProt Splice Variant

Entrez Gene

21974

UniGene

Mm.404738

RefSeq

MGI ID

MGI Symbol

Top2b

OMIM

CCDS

HPRD

IMGT

EMBL

GenPept