InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Slc4a3

Summary

InnateDB Protein

IDBP-540448.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Slc4a3

Protein Name

solute carrier family 4 (anion exchanger), member 3

Synonyms

A930038D23Rik; Ae3;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000116747

InnateDB Gene

IDBG-171856 (Slc4a3)

Protein Structure

UniProt Annotation

Function

Plasma membrane anion exchange protein.

Subcellular Localization

Membrane; Multi-pass membrane protein.

Disease Associations

Tissue Specificity

Neuronal.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.

Predicted by orthology
Total	2 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005215	transporter activity
GO:0005452	inorganic anion exchanger activity
GO:0008509	anion transmembrane transporter activity
GO:0015301	anion:anion antiporter activity

Biological Process

GO:0006810	transport
GO:0006820	anion transport
GO:0051453	regulation of intracellular pH
GO:0055085	transmembrane transport

Cellular Component

GO:0005886	plasma membrane
GO:0016020	membrane
GO:0016021	integral component of membrane

Protein Structure and Domains

PDB ID

MGI:109350

InterPro

IPR001717 Anion exchange protein
IPR002979 Anion exchange protein 3
IPR003020 Bicarbonate transporter, eukaryotic
IPR011531 Bicarbonate transporter, C-terminal
IPR013769 Band 3 cytoplasmic domain
IPR016152 Phosphotransferase/anion transporter

PFAM

PF00955
PF07565

PRINTS

PR00165
PR01189
PR01231

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

P16283