InnateDB Protein
|
IDBP-540768.3
|
Last Modified
|
2014-10-13 [Report errors or provide feedback]
|
Gene Symbol
|
Enpp5
|
Protein Name
|
ectonucleotide pyrophosphatase/phosphodiesterase 5
|
Synonyms
|
AW061004; D17Abb1e; E-NPP 5; mKIAA4152;
|
Species
|
Mus musculus
|
Ensembl Protein
|
ENSMUSP00000122767
|
InnateDB Gene
|
IDBG-184761 (Enpp5)
|
Protein Structure
|
|
Function |
May play a role in neuronal cell communication. Lacks nucleotide pyrophosphatase and lysopholipase D activity (By similarity). {ECO:0000250UniProtKB:P84039}.
|
Subcellular Localization |
Secreted {ECO:0000305}. Membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}.
|
Disease Associations |
|
Tissue Specificity |
Expressed abundantly in the brain and kidney, and at lower levels in the liver. {ECO:0000269PubMed:12927778}.
|
Comments |
|
Number of Interactions
|
This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
Experimentally validated |
Total |
3
[view]
|
Protein-Protein |
3
[view]
|
Protein-DNA |
0
|
Protein-RNA |
0
|
DNA-DNA |
0
|
RNA-RNA |
0
|
DNA-RNA |
0
|
|
|
|
Molecular Function |
|
Biological Process |
|
Cellular Component |
|
PDB ID |
MGI:1933830
|
InterPro |
IPR002591
Type I phosphodiesterase/nucleotide pyrophosphatase/phosphate transferase
IPR017850
Alkaline-phosphatase-like, core domain
|
PFAM |
PF01663
|
PRINTS |
|
PIRSF |
|
SMART |
|
TIGRFAMs |
|
Modification |
|
SwissProt |
Q9EQG7
|
PhosphoSite |
PhosphoSite-
|
TrEMBL |
|
UniProt Splice Variant |
|
Entrez Gene |
83965
|
UniGene |
Mm.488146
|
RefSeq |
NP_001162091
|
MGI ID |
|
MGI Symbol |
Enpp5
|
OMIM |
|
CCDS |
CCDS28802
|
HPRD |
|
IMGT |
|
EMBL |
AF233377
BC138977
BC138978
CT030230
|
GenPept |
AAG49143
AAI38978
AAI38979
CAP19172
|
|
|