Version 5.4
Mus musculus Protein: Tbc1d14
Summary
InnateDB Protein IDBP-540775.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Tbc1d14
Protein Name TBC1 domain family, member 14
Synonyms 2810413P16Rik; AU043625; C86258; D5Ertd110e; mKIAA1322;
Species Mus musculus
Ensembl Protein ENSMUSP00000117414
InnateDB Gene IDBG-158200 (Tbc1d14)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 2 [view]
Protein-Protein 0
Protein-DNA 2 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005097 Rab GTPase activator activity
GO:0019901 protein kinase binding
Biological Process
GO:0010507 negative regulation of autophagy
GO:0032313 regulation of Rab GTPase activity
GO:0032851 positive regulation of Rab GTPase activity
GO:2000785 regulation of autophagic vacuole assembly
Cellular Component
GO:0005776 autophagic vacuole
Protein Structure and Domains
PDB ID MGI:1098708
InterPro IPR000195 Rab-GTPase-TBC domain
PFAM PF00566
PRINTS
PIRSF
SMART SM00164
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL Q921M0
UniProt Splice Variant
Entrez Gene 102641289
UniGene
RefSeq XP_006503707
MGI ID
MGI Symbol Tbc1d14
OMIM
CCDS CCDS51480
HPRD
IMGT
EMBL AC131803 AC167815 BC011420 CH466524
GenPept AAH11420 EDL37508

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca