InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Tpr

Summary

InnateDB Protein

IDBP-541049.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Tpr

Protein Name

translocated promoter region

Synonyms

2610029M07Rik; C77892;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000117616

InnateDB Gene

IDBG-197523 (Tpr)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 15 experimentally validated interaction(s) in this database.
They are also associated with 59 interaction(s) predicted by orthology.

Experimentally validated
Total	15 [view]
Protein-Protein	15 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	59 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000166	nucleotide binding
GO:0003682	chromatin binding
GO:0003729	mRNA binding
GO:0005487	nucleocytoplasmic transporter activity
GO:0005515	protein binding
GO:0015631	tubulin binding
GO:0031072	heat shock protein binding
GO:0042803	protein homodimerization activity
GO:0044822	poly(A) RNA binding
GO:0051019	mitogen-activated protein kinase binding
GO:0070840	dynein complex binding

Biological Process

GO:0000122	negative regulation of transcription from RNA polymerase II promoter
GO:0000189	MAPK import into nucleus
GO:0006404	RNA import into nucleus
GO:0006405	RNA export from nucleus
GO:0006606	protein import into nucleus
GO:0006999	nuclear pore organization
GO:0007067	mitotic nuclear division
GO:0007094	mitotic spindle assembly checkpoint
GO:0010965	regulation of mitotic sister chromatid separation
GO:0031453	positive regulation of heterochromatin assembly
GO:0031990	mRNA export from nucleus in response to heat stress
GO:0034605	cellular response to heat
GO:0035457	cellular response to interferon-alpha
GO:0042307	positive regulation of protein import into nucleus
GO:0045947	negative regulation of translational initiation
GO:0046827	positive regulation of protein export from nucleus
GO:0046832	negative regulation of RNA export from nucleus
GO:0070849	response to epidermal growth factor
GO:0090267	positive regulation of mitotic cell cycle spindle assembly checkpoint
GO:0090316	positive regulation of intracellular protein transport
GO:1901673	regulation of spindle assembly involved in mitosis

Cellular Component

GO:0000776	kinetochore
GO:0005634	nucleus
GO:0005635	nuclear envelope
GO:0005643	nuclear pore
GO:0005737	cytoplasm
GO:0005868	cytoplasmic dynein complex
GO:0019898	extrinsic component of membrane
GO:0031965	nuclear membrane
GO:0034399	nuclear periphery
GO:0042405	nuclear inclusion body
GO:0044615	nuclear pore nuclear basket
GO:0072686	mitotic spindle