Version 5.4
Mus musculus Protein: Ermp1
Summary
InnateDB Protein IDBP-541087.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Ermp1
Protein Name endoplasmic reticulum metallopeptidase 1
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000124881
InnateDB Gene IDBG-157520 (Ermp1)
Protein Structure
UniProt Annotation
Function Within the ovary, required for the organization of somatic cells and oocytes into discrete follicular structures. {ECO:0000250}.
Subcellular Localization Endoplasmic reticulum membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0008237 metallopeptidase activity
GO:0016787 hydrolase activity
GO:0046872 metal ion binding
Biological Process
GO:0006508 proteolysis
GO:0008152 metabolic process
Cellular Component
GO:0005789 endoplasmic reticulum membrane
GO:0016020 membrane
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID MGI:106250
InterPro IPR002933 Peptidase M20
IPR007484 Peptidase M28
PFAM PF01546
PF04389
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q3UVK0
PhosphoSite PhosphoSite-Q3UVK0
TrEMBL Q8K2F9
UniProt Splice Variant
Entrez Gene 226090
UniGene Mm.472654
RefSeq NP_001074682
MGI ID
MGI Symbol Ermp1
OMIM
CCDS CCDS37952
HPRD
IMGT
EMBL AK037287 AK081674 AK129447 AK137206 BC031519 BC151181 BC151182 BC157914
GenPept AAH31519 AAI51182 AAI51183 AAI57915 BAC29784 BAC38286 BAC98257 BAE23269

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca