Mus musculus Protein: Myo9a | |||||||||||||||
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Summary | |||||||||||||||
InnateDB Protein | IDBP-541259.3 | ||||||||||||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||||||
Gene Symbol | Myo9a | ||||||||||||||
Protein Name | myosin IXa | ||||||||||||||
Synonyms | |||||||||||||||
Species | Mus musculus | ||||||||||||||
Ensembl Protein | ENSMUSP00000117432 | ||||||||||||||
InnateDB Gene | IDBG-173436 (Myo9a) | ||||||||||||||
Protein Structure | |||||||||||||||
UniProt Annotation | |||||||||||||||
Function | Myosins are actin-based motor molecules with ATPase activity. Unconventional myosins serve in intracellular movements. Regulates Rho activity in neurons, has a role in the regulation of neuronal morphology and function (By similarity). {ECO:0000250}. | ||||||||||||||
Subcellular Localization | Membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}. | ||||||||||||||
Disease Associations | |||||||||||||||
Tissue Specificity | Expressed in the eye, lung, liver, brain, heart, kidney, skeletal muscle and spleen. No detection was found in liver. {ECO:0000269PubMed:10409426}. | ||||||||||||||
Comments | |||||||||||||||
Interactions | |||||||||||||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 6 interaction(s) predicted by orthology.
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Gene Ontology | |||||||||||||||
Molecular Function |
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Biological Process |
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Cellular Component |
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Protein Structure and Domains | |||||||||||||||
PDB ID | MGI:107735 | ||||||||||||||
InterPro |
IPR000048
IQ motif, EF-hand binding site IPR000159 Ras-association IPR000198 Rho GTPase-activating protein domain IPR001609 Myosin head, motor domain IPR002219 Protein kinase C-like, phorbol ester/diacylglycerol binding IPR008936 Rho GTPase activation protein IPR027417 P-loop containing nucleoside triphosphate hydrolase IPR029071 Ubiquitin-related domain |
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PFAM |
PF00612
PF00788 PF00620 PF00063 PF00130 |
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PRINTS |
PR00193
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PIRSF | |||||||||||||||
SMART |
SM00015
SM00314 SM00324 SM00242 SM00109 |
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TIGRFAMs | |||||||||||||||
Post-translational Modifications | |||||||||||||||
Modification | |||||||||||||||
Cross-References | |||||||||||||||
SwissProt | Q8C170 | ||||||||||||||
PhosphoSite | PhosphoSite-Q8C170 | ||||||||||||||
TrEMBL | |||||||||||||||
UniProt Splice Variant | |||||||||||||||
Entrez Gene | 270163 | ||||||||||||||
UniGene | Mm.408838 | ||||||||||||||
RefSeq | XP_006511275 | ||||||||||||||
MGI ID | |||||||||||||||
MGI Symbol | Myo9a | ||||||||||||||
OMIM | |||||||||||||||
CCDS | |||||||||||||||
HPRD | |||||||||||||||
IMGT | |||||||||||||||
EMBL | AC131749 AC156795 AK028873 AK029836 AK162486 BC046526 BC096035 | ||||||||||||||
GenPept | AAH46526 AAH96035 BAC26164 BAC26639 BAE36942 | ||||||||||||||