Version 5.4
Mus musculus Protein: Tmem163
Summary
InnateDB Protein IDBP-541837.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Tmem163
Protein Name transmembrane protein 163
Synonyms 2610024A01Rik; SV31;
Species Mus musculus
Ensembl Protein ENSMUSP00000124307
InnateDB Gene IDBG-189149 (Tmem163)
Protein Structure
UniProt Annotation
Function May bind zinc and other divalent cations and recruit them to vesicular organelles. {ECO:0000250}.
Subcellular Localization Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane {ECO:0000269PubMed:17623043}; Multi- pass membrane protein {ECO:0000269PubMed:17623043}. Early endosome membrane {ECO:0000250}. Note=Glutamatergic synaptic vesicles.
Disease Associations
Tissue Specificity Specifically expressed in brain. Mainly expressed in the glutaminergic neuron subpopulations. {ECO:0000269PubMed:17623043}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0008270 zinc ion binding
Biological Process
GO:0008150 biological_process
Cellular Component
GO:0030054 cell junction
GO:0030285 integral component of synaptic vesicle membrane
GO:0031901 early endosome membrane
Protein Structure and Domains
PDB ID MGI:1919410
InterPro
PFAM
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q8C996
PhosphoSite PhosphoSite-Q8C996
TrEMBL
UniProt Splice Variant
Entrez Gene 72160
UniGene Mm.403679
RefSeq NP_082411
MGI ID
MGI Symbol Tmem163
OMIM
CCDS CCDS35696
HPRD
IMGT
EMBL AK011522 AK042650 AK047006 BC046234 BC059048
GenPept AAH46234 AAH59048 BAB27676 BAC31320 BAC32940

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca