InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Rad52

Summary

InnateDB Protein

IDBP-542021.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Rad52

Protein Name

RAD52 homolog (S. cerevisiae)

Synonyms

Rad52yh;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000125502

InnateDB Gene

IDBG-182943 (Rad52)

Protein Structure

UniProt Annotation

Function

Involved in double-stranded break repair. Plays a central role in genetic recombination and DNA repair by promoting the annealing of complementary single-stranded DNA and by stimulation of the RAD51 recombinase (By similarity). {ECO:0000250}.

Subcellular Localization

Nucleus {ECO:0000305}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 12 interaction(s) predicted by orthology.

Predicted by orthology
Total	12 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003677	DNA binding
GO:0005515	protein binding
GO:0042802	identical protein binding

Biological Process

GO:0000724	double-strand break repair via homologous recombination
GO:0006281	DNA repair
GO:0006310	DNA recombination

Cellular Component

GO:0005634

nucleus

Protein Structure and Domains

PDB ID

MGI:101949

InterPro

IPR004585 DNA recombination/repair protein Rad52
IPR007232 Rad52/22 double-strand break repair protein

PFAM

PF04098

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

P43352

PhosphoSite

PhosphoSite-P43352

TrEMBL

UniProt Splice Variant

Entrez Gene

19365

UniGene

RefSeq

NP_001159854

MGI ID

MGI Symbol

Rad52

OMIM

CCDS

CCDS51887

HPRD

IMGT

EMBL

AF004854 U06837 U12135 Z32767

GenPept

AAA75441 AAA85794 AAB69174 CAA83659