Version 5.4
Mus musculus Protein: Ttc26
Summary
InnateDB Protein IDBP-542104.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Ttc26
Protein Name tetratricopeptide repeat domain 26
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000124369
InnateDB Gene IDBG-137171 (Ttc26)
Protein Structure
UniProt Annotation
Function May play a critical role in ciliogenesis and normal cilia function. {ECO:0000269PubMed:22718903}.
Subcellular Localization Cell projection, cilium {ECO:0000269PubMed:22718903}. Note=Localizes at the base to the ciliary transition zone.
Disease Associations
Tissue Specificity High expression detected in testis. Detected also retina, kidney, lung and brain tissue. The expression level is low in liver and spleen. {ECO:0000269PubMed:22718903}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0005515 protein binding
Biological Process
GO:0008594 photoreceptor cell morphogenesis
GO:0042073 intraciliary transport
GO:0042384 cilium assembly
GO:0046530 photoreceptor cell differentiation
Cellular Component
GO:0005813 centrosome
GO:0005929 cilium
GO:0030992 intraciliary transport particle B
GO:0036064 ciliary basal body
GO:0072372 primary cilium
Protein Structure and Domains
PDB ID MGI:2444853
InterPro IPR013026 Tetratricopeptide repeat-containing domain
PFAM
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q8BS45
PhosphoSite PhosphoSite-Q8BS45
TrEMBL Q8C379
UniProt Splice Variant
Entrez Gene 264134
UniGene Mm.253446
RefSeq NP_705828
MGI ID
MGI Symbol Ttc26
OMIM
CCDS CCDS51750
HPRD
IMGT
EMBL AK035185 AK086670 BC066060
GenPept AAH66060 BAC28974 BAC39716

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca