InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Fxn

Summary

InnateDB Protein

IDBP-542114.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Fxn

Protein Name

frataxin

Synonyms

FA; FARR; Frda; X25;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000117047

InnateDB Gene

IDBG-154568 (Fxn)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.
They are also associated with 6 interaction(s) predicted by orthology.

Experimentally validated
Total	5 [view]
Protein-Protein	5 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	6 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0008199	ferric iron binding

Biological Process

GO:0006119	oxidative phosphorylation
GO:0006879	cellular iron ion homeostasis
GO:0007005	mitochondrion organization
GO:0007628	adult walking behavior
GO:0009060	aerobic respiration
GO:0009792	embryo development ending in birth or egg hatching
GO:0016226	iron-sulfur cluster assembly
GO:0019230	proprioception
GO:0040015	negative regulation of multicellular organism growth
GO:0046621	negative regulation of organ growth

Cellular Component

GO:0005739

mitochondrion

Protein Structure and Domains

PDB ID

MGI:1096879

InterPro

IPR002908 Frataxin/CyaY

PFAM

PF01491

PRINTS

PR00904

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-

TrEMBL

Q9R295

UniProt Splice Variant

Entrez Gene

14297

UniGene

Mm.7319

RefSeq

MGI ID

MGI Symbol

Fxn

OMIM

CCDS

HPRD

IMGT

EMBL

AC149224 AC165089 AF148507

GenPept

AAD30307