InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Hoxa13

Summary

InnateDB Protein

IDBP-542162.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Hoxa13

Protein Name

homeobox A13

Synonyms

Hd; Hox-1.10;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000125221

InnateDB Gene

IDBG-148096 (Hoxa13)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 7 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.

Experimentally validated
Total	7 [view]
Protein-Protein	7 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	1 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003677	DNA binding
GO:0003700	sequence-specific DNA binding transcription factor activity
GO:0005515	protein binding
GO:0043565	sequence-specific DNA binding
GO:0044212	transcription regulatory region DNA binding

Biological Process

GO:0001570	vasculogenesis
GO:0001886	endothelial cell morphogenesis
GO:0001894	tissue homeostasis
GO:0003281	ventricular septum development
GO:0006355	regulation of transcription, DNA-templated
GO:0009653	anatomical structure morphogenesis
GO:0009887	organ morphogenesis
GO:0030510	regulation of BMP signaling pathway
GO:0030539	male genitalia development
GO:0035115	embryonic forelimb morphogenesis
GO:0045840	positive regulation of mitosis
GO:0045944	positive regulation of transcription from RNA polymerase II promoter
GO:0048839	inner ear development
GO:0048844	artery morphogenesis
GO:0060442	branching involved in prostate gland morphogenesis
GO:0060847	endothelial cell fate specification
GO:2001055	positive regulation of mesenchymal cell apoptotic process

Cellular Component

GO:0005634

nucleus

Protein Structure and Domains

PDB ID

MGI:96173

InterPro

IPR001356 Homeobox domain
IPR009057 Homeodomain-like
IPR022067 Homeobox protein Hox1A3 N-terminal

PFAM

PF00046
PF12284

PRINTS

PIRSF

SMART

SM00389

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-

TrEMBL

E0CXK7

UniProt Splice Variant

Entrez Gene

15398

UniGene

Mm.377086

RefSeq

MGI ID

MGI Symbol

Hoxa13

OMIM

CCDS

HPRD

IMGT

EMBL

AC015583 FQ828346

GenPept