InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Znhit1

Summary

InnateDB Protein

IDBP-542191.4

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Znhit1

Protein Name

zinc finger, HIT domain containing 1

Synonyms

2700001K05Rik; ZNFN4A1;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000115929

InnateDB Gene

IDBG-204714 (Znhit1)

Protein Structure

UniProt Annotation

Function

Seems to play a role in p53-mediated apoptosis induction. Binds to NR1D2 and relieves it of its inhibitory effect on the transcription of APOC3 without affecting its DNA-binding activity (By similarity). {ECO:0000250}.

Subcellular Localization

Nucleus {ECO:0000250}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 11 interaction(s) predicted by orthology.

Predicted by orthology
Total	11 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003682	chromatin binding
GO:0005515	protein binding
GO:0042826	histone deacetylase binding
GO:0046872	metal ion binding

Biological Process

GO:0000122	negative regulation of transcription from RNA polymerase II promoter
GO:0031063	regulation of histone deacetylation
GO:0042129	regulation of T cell proliferation
GO:0070317	negative regulation of G0 to G1 transition