InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Tsg101

Summary

InnateDB Protein

IDBP-542509.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Tsg101

Protein Name

tumor susceptibility gene 101

Synonyms

AI255943; CC2;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000121314

InnateDB Gene

IDBG-187081 (Tsg101)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 21 experimentally validated interaction(s) in this database.
They are also associated with 127 interaction(s) predicted by orthology.

Experimentally validated
Total	21 [view]
Protein-Protein	21 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	127 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003714	transcription corepressor activity
GO:0005515	protein binding

Biological Process

GO:0001558	regulation of cell growth
GO:0006464	cellular protein modification process
GO:0007050	cell cycle arrest
GO:0008285	negative regulation of cell proliferation
GO:0015031	protein transport
GO:0030154	cell differentiation
GO:0030216	keratinocyte differentiation
GO:0045892	negative regulation of transcription, DNA-templated

Cellular Component

GO:0005634

nucleus

Protein Structure and Domains

PDB ID

MGI:106581

InterPro

IPR008883 Ubiquitin E2 variant, N-terminal
IPR016135 Ubiquitin-conjugating enzyme/RWD-like

PFAM

PF05743

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-

TrEMBL

D3Z2V5

UniProt Splice Variant

Entrez Gene

22088

UniGene

Mm.241334

RefSeq

MGI ID

MGI Symbol

Tsg101

OMIM

CCDS

HPRD

IMGT

EMBL

AC090123

GenPept