Version 5.4
Mus musculus Protein: Cln8
Summary
InnateDB Protein IDBP-542539.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Cln8
Protein Name ceroid-lipofuscinosis, neuronal 8
Synonyms mnd;
Species Mus musculus
Ensembl Protein ENSMUSP00000122765
InnateDB Gene IDBG-136384 (Cln8)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 28 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 0
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 28 [view]
Gene Ontology

Molecular Function
Accession GO Term
Biological Process
GO:0001306 age-dependent response to oxidative stress
GO:0006644 phospholipid metabolic process
GO:0006672 ceramide metabolic process
GO:0007006 mitochondrial membrane organization
GO:0007040 lysosome organization
GO:0007601 visual perception
GO:0007628 adult walking behavior
GO:0008203 cholesterol metabolic process
GO:0008306 associative learning
GO:0008344 adult locomotory behavior
GO:0008361 regulation of cell size
GO:0021522 spinal cord motor neuron differentiation
GO:0021523 somatic motor neuron differentiation
GO:0035176 social behavior
GO:0043066 negative regulation of apoptotic process
GO:0044257 cellular protein catabolic process
GO:0044265 cellular macromolecule catabolic process
GO:0044267 cellular protein metabolic process
GO:0045494 photoreceptor cell maintenance
GO:0050881 musculoskeletal movement
GO:0050884 neuromuscular process controlling posture
GO:0050885 neuromuscular process controlling balance
GO:0051348 negative regulation of transferase activity
GO:0051935 L-glutamate uptake involved in synaptic transmission
GO:0060041 retina development in camera-type eye
GO:0060052 neurofilament cytoskeleton organization
Cellular Component
GO:0005739 mitochondrion
GO:0005783 endoplasmic reticulum
GO:0005793 endoplasmic reticulum-Golgi intermediate compartment
Protein Structure and Domains
PDB ID MGI:1349447
InterPro
PFAM
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL D3Z3T9
UniProt Splice Variant
Entrez Gene 26889
UniGene Mm.467756
RefSeq
MGI ID
MGI Symbol Cln8
OMIM
CCDS
HPRD
IMGT
EMBL AC108844
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca