Version 5.4
| Mus musculus Protein: Clvs2 | |||||||||
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| Summary | |||||||||
| InnateDB Protein | IDBP-542749.3 | ||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||
| Gene Symbol | Clvs2 | ||||||||
| Protein Name | clavesin 2 | ||||||||
| Synonyms | |||||||||
| Species | Mus musculus | ||||||||
| Ensembl Protein | ENSMUSP00000125100 | ||||||||
| InnateDB Gene | IDBG-142944 (Clvs2) | ||||||||
| Protein Structure |
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| UniProt Annotation | |||||||||
| Function | Required for normal morphology of late endosomes and/or lysosomes in neurons. Binds phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2) (By similarity). {ECO:0000250}. | ||||||||
| Subcellular Localization | Golgi apparatus, trans-Golgi network membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}. Early endosome membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}. Cytoplasmic vesicle, clathrin-coated vesicle {ECO:0000250}. | ||||||||
| Disease Associations | |||||||||
| Tissue Specificity | |||||||||
| Comments | |||||||||
| Interactions | |||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
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| Gene Ontology | |||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Protein Structure and Domains | |||||||||
| PDB ID | MGI:2443223 | ||||||||
| InterPro |
IPR001071
Cellular retinaldehyde binding/alpha-tocopherol transport IPR001251 CRAL-TRIO domain IPR011074 CRAL/TRIO, N-terminal domain |
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| PFAM |
PF00650
PF13716 PF03765 |
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| PRINTS |
PR00180
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| PIRSF | |||||||||
| SMART |
SM00516
SM01100 |
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| TIGRFAMs | |||||||||
| Post-translational Modifications | |||||||||
| Modification | |||||||||
| Cross-References | |||||||||
| SwissProt | Q8BG92 | ||||||||
| PhosphoSite | PhosphoSite-Q8BG92 | ||||||||
| TrEMBL | |||||||||
| UniProt Splice Variant | |||||||||
| Entrez Gene | 215890 | ||||||||
| UniGene | Mm.94461 | ||||||||
| RefSeq | |||||||||
| MGI ID | |||||||||
| MGI Symbol | Clvs2 | ||||||||
| OMIM | |||||||||
| CCDS | |||||||||
| HPRD | |||||||||
| IMGT | |||||||||
| EMBL | AK039308 AK049896 AK053797 AK139409 AK169009 BC058539 | ||||||||
| GenPept | AAH58539 BAC30312 BAC33976 BAC35529 BAE23998 BAE40806 | ||||||||