InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Kpna6

Summary

InnateDB Protein

IDBP-542930.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Kpna6

Protein Name

karyopherin (importin) alpha 6

Synonyms

IPOA7; Kpna5; NPI-2;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000114265

InnateDB Gene

IDBG-191500 (Kpna6)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
They are also associated with 19 interaction(s) predicted by orthology.

Experimentally validated
Total	3 [view]
Protein-Protein	3 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	19 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005488	binding
GO:0005515	protein binding
GO:0008565	protein transporter activity

Biological Process

GO:0006606	protein import into nucleus
GO:0045944	positive regulation of transcription from RNA polymerase II promoter
GO:0060135	maternal process involved in female pregnancy

Cellular Component

GO:0005634	nucleus
GO:0005737	cytoplasm

Protein Structure and Domains

PDB ID

MGI:1100836

InterPro

IPR002652 Importin-alpha, importin-beta-binding domain
IPR016024 Armadillo-type fold

PFAM

PF01749

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-

TrEMBL

A2ADZ6

UniProt Splice Variant

Entrez Gene

16650

UniGene

Mm.418605

RefSeq

MGI ID

MGI Symbol

Kpna6

OMIM

CCDS

HPRD

IMGT

EMBL

AL671759

GenPept