InnateDB Protein
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IDBP-54600.7
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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ZXDC
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Protein Name
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ZXD family zinc finger C
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Synonyms
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000337694
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InnateDB Gene
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IDBG-54598 (ZXDC)
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Protein Structure
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Function |
Cooperates with CIITA to promote transcription of MHC class I and MHC class II genes. {ECO:0000269PubMed:16600381, ECO:0000269PubMed:17493635, ECO:0000269PubMed:17696781}.
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Subcellular Localization |
Nucleus {ECO:0000305}.
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Disease Associations |
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Tissue Specificity |
Expressed at high levels in heart, kidney, liver and testis, at moderate levels in brain and stomach, and at low levels in lung, muscle, placenta, small intestine and spleen. {ECO:0000269PubMed:16600381}.
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 15 experimentally validated interaction(s) in this database.
Experimentally validated |
Total |
15
[view]
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Protein-Protein |
15
[view]
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Protein-DNA |
0
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Molecular Function |
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Biological Process |
GO:0006351
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transcription, DNA-templated
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GO:0045893
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positive regulation of transcription, DNA-templated
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Cellular Component |
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PDB ID |
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InterPro |
IPR007087
Zinc finger, C2H2
IPR015880
Zinc finger, C2H2-like
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PFAM |
PF00096
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PRINTS |
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PIRSF |
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SMART |
SM00355
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TIGRFAMs |
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Modification |
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SwissProt |
Q2QGD7
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PhosphoSite |
PhosphoSite-Q2QGD7
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TrEMBL |
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UniProt Splice Variant |
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Entrez Gene |
79364
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UniGene |
Hs.440049
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RefSeq |
NP_001035743
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HUGO |
HGNC:28160
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OMIM |
615746
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CCDS |
CCDS43146
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HPRD |
14420
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IMGT |
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EMBL |
AC024558
AC073439
AK092101
AY936556
BC002940
BC012729
BC073859
DQ079590
FJ980275
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GenPept |
AAH02940
AAH12729
AAH73859
AAX23974
AAZ30918
ACR56328
BAC03805
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