Version 5.4
Homo sapiens Protein: DMRTA1
Summary
InnateDB Protein IDBP-54735.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol DMRTA1
Protein Name DMRT-like family A1
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000319651
InnateDB Gene IDBG-54733 (DMRTA1)
Protein Structure
UniProt Annotation
Function
Subcellular Localization Nucleus {ECO:0000255PROSITE- ProRule:PRU00070}.
Disease Associations
Tissue Specificity Expressed in liver, kidney, pancreas, prostate and weakly detected in testis and ovary. {ECO:0000269PubMed:11863363}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
Experimentally validated
Total 3 [view]
Protein-Protein 3 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0005515 protein binding
GO:0042803 protein homodimerization activity
GO:0043565 sequence-specific DNA binding
GO:0046872 metal ion binding
Biological Process
GO:0001541 ovarian follicle development
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
GO:0060179 male mating behavior
Cellular Component
GO:0005634 nucleus
Protein Structure and Domains
PDB ID
InterPro IPR001275 DM DNA-binding domain
IPR005173 DMRTA motif
IPR009060 UBA-like
PFAM PF00751
PF03474
PRINTS
PIRSF
SMART SM00301
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q5VZB9
PhosphoSite PhosphoSite-Q5VZB9
TrEMBL
UniProt Splice Variant
Entrez Gene 63951
UniGene Hs.371976
RefSeq NP_071443
HUGO HGNC:13826
OMIM 614803
CCDS CCDS6514
HPRD 10913
IMGT
EMBL AJ290954 AK096011 AL161730 BC130435 BC130437
GenPept AAI30436 AAI30438 BAC04672 CAC16590 CAH73857

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca