Version 5.4
Homo sapiens Protein: UCMA
Summary
InnateDB Protein IDBP-54870.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol UCMA
Protein Name upper zone of growth plate and cartilage matrix associated
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000367952
InnateDB Gene IDBG-54868 (UCMA)
Protein Structure
UniProt Annotation
Function May be involved in the negative control of osteogenic differentiation of osteochondrogenic precursor cells in peripheral zones of fetal cartilage and at the cartilage-bone interface. {ECO:0000250}.
Subcellular Localization Secreted, extracellular space, extracellular matrix {ECO:0000250}.
Disease Associations
Tissue Specificity Predominantly expressed in resting chondrocytes. {ECO:0000269PubMed:16176871}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
Biological Process
GO:0045668 negative regulation of osteoblast differentiation
Cellular Component
GO:0005578 proteinaceous extracellular matrix
GO:0005615 extracellular space
GO:0016235 aggresome
GO:0031012 extracellular matrix
GO:0048471 perinuclear region of cytoplasm
Protein Structure and Domains
PDB ID
InterPro
PFAM
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q8WVF2
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 221044
UniGene Hs.112998
RefSeq NP_660357
HUGO HGNC:25205
OMIM
CCDS CCDS31147
HPRD 12578
IMGT
EMBL AL138764 BC018068
GenPept AAH18068 CAI12909

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

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Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca