InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: FRMD4A

Summary

InnateDB Protein

IDBP-55479.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

FRMD4A

Protein Name

FERM domain containing 4A

Synonyms

Species

Homo sapiens

Ensembl Protein

ENSP00000350032

InnateDB Gene

IDBG-55477 (FRMD4A)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Cytoplasm, cytoskeleton {ECO:0000250}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.

Experimentally validated
Total	3 [view]
Protein-Protein	3 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	2 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0030674	protein binding, bridging

Biological Process

GO:0090162

establishment of epithelial cell polarity

Cellular Component

GO:0005737	cytoplasm
GO:0005856	cytoskeleton
GO:0005923	tight junction

Protein Structure and Domains

PDB ID

InterPro

IPR000299 FERM domain
IPR018979 FERM, N-terminal
IPR018980 FERM, C-terminal PH-like domain
IPR019748 FERM central domain
IPR019749 Band 4.1 domain
IPR019750 Band 4.1 family
IPR021774 Protein of unknown function DUF3338
IPR029071 Ubiquitin-related domain

PFAM

PF09379
PF09380
PF00373
PF11819

PRINTS

PR00935

PIRSF

SMART

SM00295

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt