Version 5.4
Homo sapiens Protein: ARL17A
Summary
InnateDB Protein IDBP-55504.7
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ARL17A
Protein Name ADP-ribosylation factor-like 17A
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000331563
InnateDB Gene IDBG-55500 (ARL17A)
Protein Structure
UniProt Annotation
Function GTP-binding protein that functions as an allosteric activator of the cholera toxin catalytic subunit, an ADP- ribosyltransferase. Involved in protein trafficking; may modulate vesicle budding and uncoating within the Golgi apparatus (By similarity). {ECO:0000250}.
Subcellular Localization Golgi apparatus {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
Experimentally validated
Total 3 [view]
Protein-Protein 1 [view]
Protein-DNA 2 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005525 GTP binding
Biological Process
GO:0007264 small GTPase mediated signal transduction
GO:0015031 protein transport
GO:0016192 vesicle-mediated transport
Cellular Component
GO:0005622 intracellular
GO:0005794 Golgi apparatus
Protein Structure and Domains
PDB ID
InterPro IPR006689 Small GTPase superfamily, ARF/SAR type
IPR024156 Small GTPase superfamily, ARF type
IPR027417 P-loop containing nucleoside triphosphate hydrolase
PFAM PF00025
PRINTS PR00328
PIRSF
SMART SM00177
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q8IVW1
PhosphoSite PhosphoSite-Q8IVW1
TrEMBL
UniProt Splice Variant
Entrez Gene 51326
UniGene Hs.733127
RefSeq NP_001275740
HUGO HGNC:24096
OMIM
CCDS CCDS74087
HPRD 17424
IMGT
EMBL AB209344 AF119889 AF208864 AF493886 AK315857 BC030570 BC041803
GenPept AAF64278 AAF69643 AAH30570 AAH41803 AAM12600 BAD92581 BAF98748

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca