InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: ARL17A

Summary

InnateDB Protein

IDBP-55506.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

ARL17A

Protein Name

ADP-ribosylation factor-like 17A

Synonyms

Species

Homo sapiens

Ensembl Protein

ENSP00000337478

InnateDB Gene

IDBG-55500 (ARL17A)

Protein Structure

UniProt Annotation

Function

GTP-binding protein that functions as an allosteric activator of the cholera toxin catalytic subunit, an ADP- ribosyltransferase. Involved in protein trafficking; may modulate vesicle budding and uncoating within the Golgi apparatus (By similarity). {ECO:0000250}.

Subcellular Localization

Golgi apparatus {ECO:0000250}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.

Experimentally validated
Total	3 [view]
Protein-Protein	1 [view]
Protein-DNA	2 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005525	GTP binding

Biological Process

GO:0007264	small GTPase mediated signal transduction
GO:0015031	protein transport
GO:0016192	vesicle-mediated transport

Cellular Component

GO:0005622	intracellular
GO:0005794	Golgi apparatus

Protein Structure and Domains

PDB ID

InterPro

IPR006689 Small GTPase superfamily, ARF/SAR type
IPR024156 Small GTPase superfamily, ARF type
IPR027417 P-loop containing nucleoside triphosphate hydrolase

PFAM

PF00025

PRINTS

PR00328

PIRSF

SMART

SM00177

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt