InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: EBF1

Summary

InnateDB Protein

IDBP-55767.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

EBF1

Protein Name

early B-cell factor 1

Synonyms

COE1; EBF; O/E-1; OLF1;

Species

Homo sapiens

Ensembl Protein

ENSP00000322898

InnateDB Gene

IDBG-55765 (EBF1)

Protein Structure

UniProt Annotation

Function

Transcriptional activator which recognizes variations of the palindromic sequence 5'-ATTCCCNNGGGAATT-3'. {ECO:0000250}.

Subcellular Localization

Nucleus {ECO:0000305}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 10 experimentally validated interaction(s) in this database.
They are also associated with 7 interaction(s) predicted by orthology.

Experimentally validated
Total	10 [view]
Protein-Protein	6 [view]
Protein-DNA	4 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	7 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003677	DNA binding
GO:0003700	sequence-specific DNA binding transcription factor activity
GO:0005515	protein binding
GO:0046872	metal ion binding
GO:0046983	protein dimerization activity
GO:0070742	C2H2 zinc finger domain binding

Biological Process

GO:0006351	transcription, DNA-templated
GO:0006355	regulation of transcription, DNA-templated
GO:0007275	multicellular organismal development
GO:0045893	positive regulation of transcription, DNA-templated