Version 5.4
Homo sapiens Protein: ATG2A
Summary
InnateDB Protein IDBP-55866.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ATG2A
Protein Name ATG2 autophagy related 2 homolog A (S. cerevisiae)
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000366475
InnateDB Gene IDBG-55864 (ATG2A)
Protein Structure
UniProt Annotation
Function Required for both autophagosome formation and regulation of lipid droplet morphology and dispersion. {ECO:0000269PubMed:22219374}.
Subcellular Localization Preautophagosomal structure membrane; Peripheral membrane protein. Lipid droplet.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 11 experimentally validated interaction(s) in this database.
Experimentally validated
Total 11 [view]
Protein-Protein 11 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0000045 autophagic vacuole assembly
GO:0000422 mitochondrion degradation
GO:0006995 cellular response to nitrogen starvation
GO:0044804 nucleophagy
Cellular Component
GO:0000407 pre-autophagosomal structure
GO:0005811 lipid particle
GO:0019898 extrinsic component of membrane
GO:0034045 pre-autophagosomal structure membrane
Protein Structure and Domains
PDB ID
InterPro IPR015412 Autophagy-related, C-terminal
PFAM PF09333
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q2TAZ0
PhosphoSite PhosphoSite-Q2TAZ0
TrEMBL B4DV45
UniProt Splice Variant
Entrez Gene 23130
UniGene Hs.370671
RefSeq NP_055919
HUGO HGNC:29028
OMIM
CCDS CCDS31602
HPRD 17186
IMGT
EMBL AB007864 AK126181 AK300925 AP001187 BC008593 BC027481 BC053596 BC110650 BC113091
GenPept AAH08593 AAH27481 AAH53596 AAI10651 AAI13092 BAA23700 BAC86477 BAG62557

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca