Version 5.4
Homo sapiens Protein: SNX15
Summary
InnateDB Protein IDBP-56098.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SNX15
Protein Name sorting nexin 15
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000366452
InnateDB Gene IDBG-56090 (SNX15)
Protein Structure
UniProt Annotation
Function May be involved in several stages of intracellular trafficking. Overexpression of SNX15 disrupts the normal trafficking of proteins from the plasma membrane to recycling endosomes or the TGN. {ECO:0000269PubMed:11085978}.
Subcellular Localization Cytoplasm {ECO:0000269PubMed:11085978}. Membrane {ECO:0000269PubMed:11085978}; Peripheral membrane protein {ECO:0000269PubMed:11085978}; Cytoplasmic side {ECO:0000269PubMed:11085978}. Cytoplasmic vesicle membrane {ECO:0000269PubMed:11085978}; Peripheral membrane protein {ECO:0000269PubMed:11085978}; Cytoplasmic side {ECO:0000269PubMed:11085978}.
Disease Associations
Tissue Specificity Widely expressed. {ECO:0000269PubMed:11085978}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 8 experimentally validated interaction(s) in this database.
Experimentally validated
Total 8 [view]
Protein-Protein 8 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0035091 phosphatidylinositol binding
Biological Process
GO:0006886 intracellular protein transport
Cellular Component
GO:0005730 nucleolus
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0016020 membrane
GO:0030659 cytoplasmic vesicle membrane
Protein Structure and Domains
PDB ID
InterPro IPR001683 Phox homologous domain
IPR007330 MIT
PFAM PF00787
PF04212
PRINTS
PIRSF
SMART SM00312
SM00745
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9NRS6
PhosphoSite PhosphoSite-Q9NRS6
TrEMBL E5KQS5
UniProt Splice Variant
Entrez Gene 29907
UniGene Hs.80132
RefSeq NP_037438
HUGO HGNC:14978
OMIM 605964
CCDS CCDS8089
HPRD 12073
IMGT
EMBL AF175267 AF175268 AP000436 AP003068 BC009897 BC012767 BC014520 BT006631 CH471076 HQ205586 HQ205587 HQ205588 HQ205589 HQ205590 HQ205591 HQ205592 HQ205593 HQ205594 HQ205595 HQ205596 HQ205597 HQ205598 HQ205599 HQ205600 HQ205601 HQ205602 HQ205603 HQ205604 HQ205605 HQ205606 HQ205607 HQ205608 HQ205609 HQ205610 HQ205611 HQ205612 HQ205613 HQ205614 HQ205615 HQ205616 HQ205617 HQ205618 HQ205619 HQ205620 HQ205621 HQ205622 HQ205623 HQ205624 HQ205625
GenPept AAF89955 AAF89956 AAH09897 AAH12767 AAH14520 AAP35277 ADP91254 ADP91255 ADP91256 ADP91257 ADP91258 ADP91259 ADP91260 ADP91261 ADP91262 ADP91263 ADP91264 ADP91265 ADP91266 ADP91267 ADP91268 ADP91269 ADP91270 ADP91271 ADP91272 ADP91273 ADP91274 ADP91275 ADP91276 ADP91277 ADP91278 ADP91279 ADP91280 ADP91281 ADP91282 ADP91283 ADP91284 ADP91285 ADP91286 ADP91287 ADP91288 ADP91289 ADP91290 ADP91291 ADP91292 ADP91293 ADP91294 ADP91295 ADP91296 ADP91297 ADP91298 ADP91299 ADP91300 ADP91301 ADP91302 ADP91303 ADP91304 ADP91305 ADP91306 ADP91307 ADP91308 ADP91309 ADP91310 ADP91311 ADP91312 ADP91313 ADP91314 ADP91315 ADP91316 ADP91317 ADP91318 ADP91319 ADP91320 ADP91321 ADP91322 ADP91323 ADP91324 ADP91325 ADP91326 ADP91327 ADP91328 ADP91329 ADP91330 ADP91331 ADP91332 ADP91333 EAW74334

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca