InnateDB Protein
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IDBP-56245.7
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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NAALADL1
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Protein Name
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N-acetylated alpha-linked acidic dipeptidase-like 1
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Synonyms
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I100; NAALADASEL;
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000347955
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InnateDB Gene
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IDBG-56237 (NAALADL1)
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Protein Structure
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Function |
NAALADase-like activity unknown. Has no NAAG hydrolyzing activity. Exhibits a dipeptidyl-peptidase IV type activity. In vitro, cleaves Gly-Pro-AMC (By similarity). {ECO:0000250}.
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Subcellular Localization |
Apical cell membrane; Single-pass type II membrane protein. Note=Ileal brush border membrane.
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Disease Associations |
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Tissue Specificity |
Mainly expressed in the distal small intestine. Also expressed in the spleen and testis. Weak expression in the brain, locating mainly to the brain stem, amygdala, thalamus and ventral striatum. Isoform 2 and 3 isoform 3 are found in the small intestine and colon.
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
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Molecular Function |
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Biological Process |
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Cellular Component |
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PDB ID |
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InterPro |
IPR007365
Transferrin receptor-like, dimerisation domain
IPR007484
Peptidase M28
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PFAM |
PF04253
PF04389
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PRINTS |
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PIRSF |
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
Q9UQQ1
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PhosphoSite |
PhosphoSite-Q9UQQ1
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TrEMBL |
E9PRC7
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UniProt Splice Variant |
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Entrez Gene |
10004
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UniGene |
Hs.13967
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RefSeq |
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HUGO |
HGNC:23536
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OMIM |
602640
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CCDS |
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HPRD |
07212
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IMGT |
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EMBL |
AF010141
AJ012371
AP003068
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GenPept |
AAB87645
CAB39968
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