InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: SFXN5

Summary

InnateDB Protein

IDBP-56268.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

SFXN5

Protein Name

sideroflexin 5

Synonyms

Species

Homo sapiens

Ensembl Protein

ENSP00000272433

InnateDB Gene

IDBG-56266 (SFXN5)

Protein Structure

UniProt Annotation

Function

Transports citrate. Potential iron transporter (By similarity). {ECO:0000250}.

Subcellular Localization

Mitochondrion membrane {ECO:0000250}; Multi- pass membrane protein {ECO:0000250}.

Disease Associations

Tissue Specificity

Primarily expressed in the brain. {ECO:0000269PubMed:12039050}.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.

Gene Ontology

Molecular Function

Accession	GO Term
GO:0008324	cation transmembrane transporter activity
GO:0015137	citrate transmembrane transporter activity

Biological Process

GO:0006812	cation transport
GO:0015746	citrate transport
GO:0055072	iron ion homeostasis
GO:0055085	transmembrane transport

Cellular Component

GO:0005739	mitochondrion
GO:0005743	mitochondrial inner membrane
GO:0016020	membrane
GO:0016021	integral component of membrane

Protein Structure and Domains

PDB ID

InterPro

IPR004686 Tricarboxylate/iron carrier

PFAM

PF03820

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q8TD22

PhosphoSite

PhosphoSite-Q8TD22

TrEMBL

UniProt Splice Variant

Entrez Gene

94097

UniGene

RefSeq

NP_653180

HUGO

HGNC:16073

OMIM

615572

CCDS

CCDS1922

HPRD

18047

IMGT

EMBL

AC012366 AK289731 AY044437 BC101311 BC101312 BC101313 CH471053

GenPept

AAI01312 AAI01313 AAI01314 AAK95826 AAY14745 BAF82420 EAW99754