InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: HOXB2

Summary

InnateDB Protein

IDBP-56723.5

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

HOXB2

Protein Name

homeobox B2

Synonyms

Hox-2.8; HOX2; HOX2H; K8;

Species

Homo sapiens

Ensembl Protein

ENSP00000331741

InnateDB Gene

IDBG-56721 (HOXB2)

Protein Structure

UniProt Annotation

Function

Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. {ECO:0000269PubMed:10595394}.

Subcellular Localization

Nucleus.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.

Experimentally validated
Total	3 [view]
Protein-Protein	2 [view]
Protein-DNA	1 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003677	DNA binding
GO:0003700	sequence-specific DNA binding transcription factor activity
GO:0043565	sequence-specific DNA binding

Biological Process

GO:0002011	morphogenesis of an epithelial sheet
GO:0006351	transcription, DNA-templated
GO:0006355	regulation of transcription, DNA-templated
GO:0007275	multicellular organismal development
GO:0008015	blood circulation
GO:0009952	anterior/posterior pattern specification
GO:0009953	dorsal/ventral pattern formation
GO:0021569	rhombomere 3 development
GO:0021570	rhombomere 4 development
GO:0021612	facial nerve structural organization
GO:0048704	embryonic skeletal system morphogenesis
GO:0048705	skeletal system morphogenesis
GO:0048857	neural nucleus development