Version 5.4
Homo sapiens Protein: APOL4
Summary
InnateDB Protein IDBP-5674.7
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol APOL4
Protein Name apolipoprotein L, 4
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000333229
InnateDB Gene IDBG-5672 (APOL4)
Protein Structure
UniProt Annotation
Function May play a role in lipid exchange and transport throughout the body. May participate in reverse cholesterol transport from peripheral cells to the liver (By similarity). {ECO:0000250}.
Subcellular Localization Secreted {ECO:0000305}.
Disease Associations
Tissue Specificity Widely expressed; the highest levels are in spinal cord, placenta, adrenal gland; also detected in spleen, bone marrow, uterus, trachea, mammary gland and testis; levels are low in brain, heart and pancreas.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
Experimentally validated
Total 2 [view]
Protein-Protein 1 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0008289 lipid binding
Biological Process
GO:0006629 lipid metabolic process
GO:0006869 lipid transport
GO:0042157 lipoprotein metabolic process
Cellular Component
GO:0005575 cellular_component
GO:0005576 extracellular region
GO:0005615 extracellular space
Protein Structure and Domains
PDB ID
InterPro IPR008405 Apolipoprotein L
PFAM PF05461
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9BPW4
PhosphoSite PhosphoSite-Q9BPW4
TrEMBL F5H1P9
UniProt Splice Variant
Entrez Gene 80832
UniGene Hs.115099
RefSeq
HUGO HGNC:14867
OMIM 607254
CCDS CCDS74851
HPRD 16237
IMGT
EMBL AF305226 AY014909 AY014910 AY014911 AY014912 AY014913 AY014914 AY014915 Z95114
GenPept AAG50350 AAG50351 AAG50352 AAG50353 AAK20212

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca