InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: HOXB8

Summary

InnateDB Protein

IDBP-56952.5

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

HOXB8

Protein Name

homeobox B8

Synonyms

Hox-2.4; HOX2; HOX2D;

Species

Homo sapiens

Ensembl Protein

ENSP00000239144

InnateDB Gene

IDBG-56950 (HOXB8)

Protein Structure

UniProt Annotation

Function

Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

Subcellular Localization

Nucleus.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 17 interaction(s) predicted by orthology.

Experimentally validated
Total	2 [view]
Protein-Protein	2 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	17 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000976	transcription regulatory region sequence-specific DNA binding
GO:0003677	DNA binding
GO:0003700	sequence-specific DNA binding transcription factor activity

Biological Process

GO:0006351	transcription, DNA-templated
GO:0006355	regulation of transcription, DNA-templated
GO:0007625	grooming behavior
GO:0008344	adult locomotory behavior
GO:0009952	anterior/posterior pattern specification
GO:0019233	sensory perception of pain
GO:0021516	dorsal spinal cord development
GO:0045638	negative regulation of myeloid cell differentiation
GO:0048704	embryonic skeletal system morphogenesis
GO:0048705	skeletal system morphogenesis