InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: CASK

Summary

InnateDB Protein

IDBP-57629.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

CASK

Protein Name

calcium/calmodulin-dependent serine protein kinase (MAGUK family)

Synonyms

CAGH39; CAMGUK; CMG; FGS4; LIN2; MICPCH; MRXSNA; TNRC8;

Species

Homo sapiens

Ensembl Protein

ENSP00000367421

InnateDB Gene

IDBG-57627 (CASK)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 81 experimentally validated interaction(s) in this database.
They are also associated with 6 interaction(s) predicted by orthology.

Experimentally validated
Total	81 [view]
Protein-Protein	80 [view]
Protein-DNA	0
Protein-RNA	1 [view]
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	6 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding

Biological Process

Cellular Component

Protein Structure and Domains

PDB ID

InterPro

IPR001452 SH3 domain
IPR001478 PDZ domain
IPR004172 L27
IPR008144 Guanylate kinase-like
IPR008145 Guanylate kinase/L-type calcium channel beta subunit
IPR011511 Variant SH3 domain
IPR014775 L27, C-terminal
IPR027417 P-loop containing nucleoside triphosphate hydrolase

PFAM