Version 5.4
Homo sapiens Protein: RSU1
Summary
InnateDB Protein IDBP-57670.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol RSU1
Protein Name Ras suppressor protein 1
Synonyms RSP-1;
Species Homo sapiens
Ensembl Protein ENSP00000367154
InnateDB Gene IDBG-57666 (RSU1)
Protein Structure
UniProt Annotation
Function Potentially plays a role in the Ras signal transduction pathway. Capable of suppressing v-Ras transformation in vitro.
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 21 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 21 [view]
Protein-Protein 19 [view]
Protein-DNA 2 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0007165 signal transduction
GO:0007265 Ras protein signal transduction
GO:0034329 cell junction assembly
GO:2000179 positive regulation of neural precursor cell proliferation
Cellular Component
GO:0005829 cytosol
GO:0070062 extracellular vesicular exosome
Protein Structure and Domains
PDB ID
InterPro IPR001611 Leucine-rich repeat
IPR003591 Leucine-rich repeat, typical subtype
PFAM PF00560
PF13504
PF13855
PRINTS
PIRSF
SMART SM00369
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q15404
PhosphoSite PhosphoSite-Q15404
TrEMBL
UniProt Splice Variant
Entrez Gene 6251
UniGene Hs.706132
RefSeq
HUGO HGNC:10464
OMIM 179555
CCDS CCDS7112
HPRD 01551
IMGT
EMBL AC073367 AK292911 AK312520 AL365215 BC005993 BC008691 BC015644 CH471072 CR536521 CR541840 EF445013 L12535
GenPept AAA60292 AAH05993 AAH08691 AAH15644 ACA06048 ACA06049 ACA06050 BAF85600 BAG35419 CAG38758 CAG46639 CAH73632 CAH73633 EAW86222 EAW86223 EAW86224

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca