Version 5.4
Homo sapiens Protein: NXPH3
Summary
InnateDB Protein IDBP-57706.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol NXPH3
Protein Name neurexophilin 3
Synonyms NPH3;
Species Homo sapiens
Ensembl Protein ENSP00000329295
InnateDB Gene IDBG-57704 (NXPH3)
Protein Structure
UniProt Annotation
Function May be signaling molecules that resemble neuropeptides. Ligand for alpha-neurexins (By similarity). {ECO:0000250}.
Subcellular Localization Secreted {ECO:0000305}.
Disease Associations
Tissue Specificity Highest level in brain.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
Experimentally validated
Total 3 [view]
Protein-Protein 3 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0005102 receptor binding
Biological Process
GO:0007218 neuropeptide signaling pathway
Cellular Component
GO:0005576 extracellular region
Protein Structure and Domains
PDB ID
InterPro IPR010450 Neurexophilin
IPR026845 Neurexophilin/NXPE
PFAM PF06312
PRINTS
PIRSF PIRSF038019
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt O95157
PhosphoSite PhosphoSite-O95157
TrEMBL
UniProt Splice Variant
Entrez Gene 11248
UniGene Hs.55069
RefSeq NP_009156
HUGO HGNC:8077
OMIM 604636
CCDS CCDS11550
HPRD 06865
IMGT
EMBL AB032985 AF043468 AL834282 AY358526 BC022541 CH471109
GenPept AAD02281 AAH22541 AAQ88890 BAA86473 CAD38956 EAW94676

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca