InnateDB Protein
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IDBP-57856.4
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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SLC24A3
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Protein Name
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solute carrier family 24 (sodium/potassium/calcium exchanger), member 3
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Synonyms
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000333519
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InnateDB Gene
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IDBG-57854 (SLC24A3)
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Protein Structure
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Function |
Transports 1 Ca(2+) and 1 K(+) in exchange for 4 Na(+). {ECO:0000250}.
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Subcellular Localization |
Membrane; Multi-pass membrane protein.
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Disease Associations |
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Tissue Specificity |
Abundant in the brain. Expressed at low levels in the aorta, uterus and intestine.
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
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Molecular Function |
Accession |
GO Term |
GO:0008273
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calcium, potassium:sodium antiporter activity
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GO:0015293
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symporter activity
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Biological Process |
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Cellular Component |
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PDB ID |
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InterPro |
IPR004481
Sodium/potassium/calcium exchanger
IPR004837
Sodium/calcium exchanger membrane region
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PFAM |
PF01699
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PRINTS |
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PIRSF |
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
Q9HC58
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PhosphoSite |
PhosphoSite-Q9HC58
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TrEMBL |
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UniProt Splice Variant |
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Entrez Gene |
57419
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UniGene |
Hs.654790
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RefSeq |
NP_065740
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HUGO |
HGNC:10977
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OMIM |
609839
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CCDS |
CCDS13140
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HPRD |
15352
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IMGT |
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EMBL |
AF169257
AF288087
AL034425
AL049647
AL121761
AL121830
AL136090
AL139429
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GenPept |
AAG12988
CAC12640
CAC13155
CAC36050
CAC36051
CAC36052
CAI17163
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