InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: NAA20

Summary

InnateDB Protein

IDBP-58033.5

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

NAA20

Protein Name

N(alpha)-acetyltransferase 20, NatB catalytic subunit

Synonyms

Species

Homo sapiens

Ensembl Protein

ENSP00000335636

InnateDB Gene

IDBG-58031 (NAA20)

Protein Structure

UniProt Annotation

Function

Catalytic subunit of the NatB complex which catalyzes acetylation of the N-terminal methionine residues of peptides beginning with Met-Asp, Met-Glu, Met-Asn and Met-Gln. Proteins with cell cycle functions are overrepresented in the pool of NatB substrates. Required for maintaining the structure and function of actomyosin fibers and for proper cellular migration. {ECO:0000269PubMed:18570629}.

Subcellular Localization

Cytoplasm {ECO:0000269PubMed:18570629}. Nucleus {ECO:0000269PubMed:18570629}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 9 experimentally validated interaction(s) in this database.

Experimentally validated
Total	9 [view]
Protein-Protein	8 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	1 [view]
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004596	peptide alpha-N-acetyltransferase activity
GO:0008080	N-acetyltransferase activity
GO:0016747	transferase activity, transferring acyl groups other than amino-acyl groups