Homo sapiens Protein: NME9
Summary
InnateDB Protein IDBP-58321.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol NME9
Protein Name NME gene family member 9
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000335444
InnateDB Gene IDBG-58315 (NME9)
Protein Structure
UniProt Annotation
Function May be a regulator of microtubule physiology.
Subcellular Localization Cytoplasm {ECO:0000250}. Cytoplasm, cytoskeleton {ECO:0000250}. Note=Associated with microtubules. Detected in cilia of lung epithelium, and associated with the spermatid tail and manchette (By similarity). {ECO:0000250}.
Disease Associations
Tissue Specificity Detected at very low levels in testis, lung and brain. {ECO:0000269PubMed:12569107}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0004550 nucleoside diphosphate kinase activity
GO:0005524 ATP binding
Biological Process
GO:0006165 nucleoside diphosphate phosphorylation
GO:0006183 GTP biosynthetic process
GO:0006228 UTP biosynthetic process
GO:0006241 CTP biosynthetic process
GO:0045454 cell redox homeostasis
Cellular Component
GO:0005737 cytoplasm
GO:0005856 cytoskeleton
Protein Structure and Domains
PDB ID
InterPro IPR001564 Nucleoside diphosphate kinase
IPR012336 Thioredoxin-like fold
IPR013766 Thioredoxin domain
PFAM PF00334
PF13098
PF13192
PF13462
PF13905
PF00085
PRINTS PR01243
PIRSF
SMART SM00562
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q86XW9
PhosphoSite PhosphoSite-Q86XW9
TrEMBL C9JXP5
UniProt Splice Variant
Entrez Gene 347736
UniGene Hs.660992
RefSeq XP_005247486
HUGO HGNC:21343
OMIM
CCDS
HPRD 18250
IMGT
EMBL AC022337 AC068777 AF196568 AK094830 AY336746
GenPept AAG28497 AAQ16116 BAC04430