Version 5.4
Homo sapiens Protein: GJB7
Summary
InnateDB Protein IDBP-583583.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol GJB7
Protein Name gap junction protein, beta 7, 25kDa
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000435355
InnateDB Gene IDBG-94108 (GJB7)
Protein Structure
UniProt Annotation
Function One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. {ECO:0000250}.
Subcellular Localization Cell membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. Cell junction, gap junction {ECO:0000250}.
Disease Associations
Tissue Specificity Weakly expressed in placenta. {ECO:0000269PubMed:12881038}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
Biological Process
GO:0007154 cell communication
Cellular Component
GO:0005922 connexon complex
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID
InterPro IPR000500 Connexin
IPR013092 Connexin, N-terminal
IPR019570 Gap junction protein, cysteine-rich domain
PFAM PF00029
PF10582
PRINTS PR00206
PIRSF
SMART SM00037
SM01089
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q6PEY0
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 375519
UniGene Hs.601385
RefSeq NP_940970
HUGO HGNC:16690
OMIM 611921
CCDS CCDS5008
HPRD 13579
IMGT
EMBL AJ414563 AK127554 AL160258 BC057813
GenPept AAH57813 BAG54522 CAC93845 CAH70467

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca