Version 5.4
Homo sapiens Protein: NAA30
Summary
InnateDB Protein IDBP-583584.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol NAA30
Protein Name N(alpha)-acetyltransferase 30, NatC catalytic subunit
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000452521
InnateDB Gene IDBG-7626 (NAA30)
Protein Structure
UniProt Annotation
Function Catalytic subunit of the N-terminal acetyltransferase C (NatC) complex. Catalyzes acetylation of the N-terminal methionine residues of peptides beginning with Met-Leu-Ala and Met-Leu-Gly. Necessary for the lysosomal localization and function of ARL8B sugeesting that ARL8B is a NatC substrate. {ECO:0000269PubMed:19398576}.
Subcellular Localization Cytoplasm {ECO:0000269PubMed:19398576}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.
Experimentally validated
Total 5 [view]
Protein-Protein 5 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0004596 peptide alpha-N-acetyltransferase activity
GO:0005515 protein binding
GO:0008080 N-acetyltransferase activity
GO:0016747 transferase activity, transferring acyl groups other than amino-acyl groups
Biological Process
GO:0008152 metabolic process
Cellular Component
GO:0005737 cytoplasm
GO:0005844 polysome
GO:0031417 NatC complex
Protein Structure and Domains
PDB ID
InterPro IPR000182 GNAT domain
IPR013653 FR47-like
IPR016181 Acyl-CoA N-acyltransferase
PFAM PF00583
PF13302
PF13508
PF13673
PF13718
PF08445
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q147X3
PhosphoSite PhosphoSite-Q147X3
TrEMBL B4DK34
UniProt Splice Variant
Entrez Gene 122830
UniGene Hs.717806
RefSeq NP_001011713
HUGO HGNC:19844
OMIM
CCDS CCDS32088
HPRD 16619
IMGT
EMBL AK296372 AL355834 BC118589 BC122557 CH471061
GenPept AAI18590 AAI22558 BAG59046 EAW80704 EAW80705

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca