Version 5.4
| Homo sapiens Protein: DBX1 | |||||||||
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| Summary | |||||||||
| InnateDB Protein | IDBP-584649.2 | ||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||
| Gene Symbol | DBX1 | ||||||||
| Protein Name | developing brain homeobox 1 | ||||||||
| Synonyms | |||||||||
| Species | Homo sapiens | ||||||||
| Ensembl Protein | ENSP00000436881 | ||||||||
| InnateDB Gene | IDBG-35841 (DBX1) | ||||||||
| Protein Structure |
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| UniProt Annotation | |||||||||
| Function | Could have a role in patterning the central nervous system during embryogenesis. Has a key role in regulating the distinct phenotypic features that distinguish two major classes of ventral interneurons, V0 and V1 neurons. Regulates the transcription factor profile, neurotransmitter phenotype, intraspinal migratory path and axonal trajectory of V0 neurons, features that differentiate them from an adjacent set of V1 neurons (By similarity). {ECO:0000250}. | ||||||||
| Subcellular Localization | Nucleus {ECO:0000255PROSITE- ProRule:PRU00108}. | ||||||||
| Disease Associations | |||||||||
| Tissue Specificity | |||||||||
| Comments | |||||||||
| Interactions | |||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
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| Gene Ontology | |||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Protein Structure and Domains | |||||||||
| PDB ID | |||||||||
| InterPro |
IPR000047
Helix-turn-helix motif IPR001356 Homeobox domain IPR009057 Homeodomain-like IPR020479 Homeodomain, metazoa |
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| PFAM |
PF00046
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| PRINTS |
PR00031
PR00024 |
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| PIRSF | |||||||||
| SMART |
SM00389
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| TIGRFAMs | |||||||||
| Post-translational Modifications | |||||||||
| Modification | |||||||||
| Cross-References | |||||||||
| SwissProt | A6NMT0 | ||||||||
| PhosphoSite | PhosphoSite-A6NMT0 | ||||||||
| TrEMBL | |||||||||
| UniProt Splice Variant | |||||||||
| Entrez Gene | 120237 | ||||||||
| UniGene | Hs.558604 | ||||||||
| RefSeq | NP_001025036 | ||||||||
| HUGO | HGNC:33185 | ||||||||
| OMIM | |||||||||
| CCDS | |||||||||
| HPRD | 18721 | ||||||||
| IMGT | |||||||||
| EMBL | AC068860 | ||||||||
| GenPept | |||||||||