Version 5.4
Homo sapiens Protein: SLC25A11
Summary
InnateDB Protein IDBP-585301.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SLC25A11
Protein Name solute carrier family 25 (mitochondrial carrier; oxoglutarate carrier), member 11
Synonyms OGC; SLC20A4;
Species Homo sapiens
Ensembl Protein ENSP00000440804
InnateDB Gene IDBG-20165 (SLC25A11)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 28 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 28 [view]
Protein-Protein 26 [view]
Protein-DNA 2 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0015367 oxoglutarate:malate antiporter activity
GO:0044822 poly(A) RNA binding
Biological Process
GO:0005975 carbohydrate metabolic process
GO:0006006 glucose metabolic process
GO:0006094 gluconeogenesis
GO:0006810 transport
GO:0015742 alpha-ketoglutarate transport
GO:0044281 small molecule metabolic process
Cellular Component
GO:0005634 nucleus
GO:0005739 mitochondrion
GO:0005743 mitochondrial inner membrane
GO:0005887 integral component of plasma membrane
Protein Structure and Domains
PDB ID
InterPro IPR018108 Mitochondrial substrate/solute carrier
IPR023395 Mitochondrial carrier domain
PFAM PF00153
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q02978
PhosphoSite PhosphoSite-Q02978
TrEMBL
UniProt Splice Variant
Entrez Gene 8402
UniGene Hs.184877
RefSeq NP_001158890
HUGO HGNC:10981
OMIM 604165
CCDS CCDS54069
HPRD 05003
IMGT
EMBL AC004771 AF070548 BC006508 BC006519 BC016294 BC017170 X66114
GenPept AAC28637 AAH06508 AAH06519 AAH16294 AAH17170 CAA46905

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca