Version 5.4
Homo sapiens Protein: LRRK1
Summary
InnateDB Protein IDBP-585374.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol LRRK1
Protein Name leucine-rich repeat kinase 1
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000431668
InnateDB Gene IDBG-32229 (LRRK1)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 83 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Experimentally validated
Total 83 [view]
Protein-Protein 82 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
Cellular Component
Protein Structure and Domains
PDB ID
InterPro IPR001611 Leucine-rich repeat
IPR002110 Ankyrin repeat
IPR003591 Leucine-rich repeat, typical subtype
IPR020683 Ankyrin repeat-containing domain
PFAM PF00560
PF13504
PF13855
PF00023
PF13606
PF11929
PF12796
PRINTS PR01415
PIRSF
SMART SM00248
SM00369
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL E9PLF8
UniProt Splice Variant
Entrez Gene 79705
UniGene Hs.640589
RefSeq
HUGO HGNC:18608
OMIM 610986
CCDS
HPRD 14319
IMGT
EMBL AC015712 AC090907
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca