Version 5.4
Homo sapiens Protein: ITGB8
Summary
InnateDB Protein IDBP-585427.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ITGB8
Protein Name integrin, beta 8
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000441561
InnateDB Gene IDBG-9181 (ITGB8)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
Experimentally validated
Total 3 [view]
Protein-Protein 2 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0004872 receptor activity
Biological Process
GO:0007160 cell-matrix adhesion
GO:0007229 integrin-mediated signaling pathway
Cellular Component
GO:0008305 integrin complex
Protein Structure and Domains
PDB ID
InterPro IPR002035 von Willebrand factor, type A
IPR002369 Integrin beta subunit, N-terminal
IPR013111 EGF-like domain, extracellular
IPR015812 Integrin beta subunit
PFAM PF00092
PF00362
PF07974
PRINTS PR01186
PIRSF PIRSF002512
SMART SM00327
SM00187
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL B4DHD4
UniProt Splice Variant
Entrez Gene 3696
UniGene Hs.686110
RefSeq
HUGO HGNC:6163
OMIM 604160
CCDS
HPRD 05001
IMGT
EMBL AC004130 AK295044
GenPept BAG58095

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca