InnateDB Protein
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IDBP-585463.3
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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FOXRED1
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Protein Name
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FAD-dependent oxidoreductase domain containing 1
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Synonyms
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000434178
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InnateDB Gene
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IDBG-75781 (FOXRED1)
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Protein Structure
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Function |
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Subcellular Localization |
Membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}.
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Disease Associations |
Mitochondrial complex I deficiency (MT-C1D) [MIM:252010]: A disorder of the mitochondrial respiratory chain that causes a wide range of clinical manifestations from lethal neonatal disease to adult-onset neurodegenerative disorders. Phenotypes include macrocephaly with progressive leukodystrophy, non-specific encephalopathy, cardiomyopathy, myopathy, liver disease, Leigh syndrome, Leber hereditary optic neuropathy, and some forms of Parkinson disease. {ECO:0000269PubMed:20818383}. Note=The disease is caused by mutations affecting the gene represented in this entry.
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Tissue Specificity |
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
Experimentally validated |
Total |
3
[view]
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Protein-Protein |
2
[view]
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Protein-DNA |
1
[view]
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Molecular Function |
Accession |
GO Term |
GO:0016491
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oxidoreductase activity
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Biological Process |
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Cellular Component |
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PDB ID |
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InterPro |
IPR006076
FAD dependent oxidoreductase
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PFAM |
PF01266
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PRINTS |
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PIRSF |
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
Q96CU9
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PhosphoSite |
PhosphoSite-Q96CU9
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TrEMBL |
B4DXM1
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UniProt Splice Variant |
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Entrez Gene |
55572
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UniGene |
Hs.317190
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RefSeq |
XP_006718942
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HUGO |
HGNC:26927
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OMIM |
613622
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CCDS |
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HPRD |
13620
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IMGT |
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EMBL |
AF103801
AF447877
AK023987
AK295267
AK298807
AK302039
AL136923
AP001318
BC002910
BC013902
CH471065
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GenPept |
AAF02421
AAH02910
AAH13902
AAQ04652
BAG51246
BAG58254
BAG60942
BAG63433
CAB66857
EAW67683
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