Homo sapiens Protein: PCDHA6
Summary
InnateDB Protein IDBP-585531.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PCDHA6
Protein Name protocadherin alpha 6
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000433378
InnateDB Gene IDBG-49721 (PCDHA6)
Protein Structure
UniProt Annotation
Function Potential calcium-dependent cell-adhesion protein. May be involved in the establishment and maintenance of specific neuronal connections in the brain.
Subcellular Localization Isoform 1: Cell membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}.Isoform 2: Secreted {ECO:0000305}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
Experimentally validated
Total 3 [view]
Protein-Protein 3 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005509 calcium ion binding
Biological Process
GO:0007155 cell adhesion
GO:0007156 homophilic cell adhesion
GO:0007399 nervous system development
Cellular Component
GO:0005576 extracellular region
GO:0005887 integral component of plasma membrane
GO:0016020 membrane
Protein Structure and Domains
PDB ID
InterPro IPR002126 Cadherin
IPR013164 Cadherin, N-terminal
IPR015919 Cadherin-like
PFAM PF00028
PF08266
PRINTS PR00205
PIRSF
SMART SM00112
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9UN73
PhosphoSite PhosphoSite-Q9UN73
TrEMBL
UniProt Splice Variant
Entrez Gene 56142
UniGene
RefSeq NP_061732
HUGO HGNC:8672
OMIM 606312
CCDS CCDS47281
HPRD 07324
IMGT
EMBL AC005609 AF152314 AF152484 AF169694 BC036674
GenPept AAC34320 AAD43708 AAD43745 AAF89691 AAH36674