Version 5.4
Homo sapiens Protein: SYNE2
Summary
InnateDB Protein IDBP-585737.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SYNE2
Protein Name spectrin repeat containing, nuclear envelope 2
Synonyms EDMD5; Nesp2; Nesprin-2; NUA; NUANCE; SYNE-2; TROPH;
Species Homo sapiens
Ensembl Protein ENSP00000450605
InnateDB Gene IDBG-8789 (SYNE2)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 27 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Experimentally validated
Total 27 [view]
Protein-Protein 27 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003779 actin binding
GO:0005515 protein binding
Biological Process
Cellular Component
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID
InterPro IPR002017 Spectrin repeat
IPR012315 KASH domain
IPR018159 Spectrin/alpha-actinin
PFAM PF00435
PF10541
PRINTS
PIRSF
SMART SM00150
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL Q86YP9
UniProt Splice Variant
Entrez Gene 23224
UniGene Hs.740777
RefSeq
HUGO HGNC:17084
OMIM 608442
CCDS
HPRD 09763
IMGT
EMBL AL162832 AL355094 AL359235 AY184205
GenPept AAO27773

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca